As we begin to age, our skin undergoes changes, losing elasticity, developing fine lines and wrinkles, and showing signs of damage such as hollowness, acne scars, hyperpigmentation, or rosacea. Luckily, advancements in aesthetic treatment have introduced major innovative solutions like Plenhyage, a cutting-edge injectable gel designed to rejuvenate and repair your skin. If you are looking for a transformative treatment that goes beyond traditional skin boosters, Plenhyage might be the perfect choice for you. At Instabeauty Aesthetics, your trusted aesthetic clinic in Cambridge, we are always on the lookout for advanced, science-backed treatments that offer great long-lasting results.

What is Plenhyage?

Plenhyage is a regenerative injectable treatment composed of polynucleotides derived from purified salmon DNA. Unlike traditional skin boosters, such as Profhilo, Jalupro, Seventy hyal 2000, Lumi eye, which are typically hyaluronic acid that bind to water, Plenhyage doesn’t. It’s DNA fragments stimulate fibroblasts and stem cells. This unique formula promotes tissue repair, boosts collagen production, enhances elasticity, and hydrates the skin, creating a healthier and more youthful appearance.

This treatment is versatile and can address multiple concerns:

  • Fine lines and wrinkles
  • Acne scarring
  • Hyperpigmentation
  • Rosacea
  • Stretch marks
  • Loss of skin elasticity
  • Great for puffy or hallow under eyea area

Plenhyage is great for the under eye area, face, neck, inner arms, thighs, knees, and even the scalp for hair restoration.

  1. Acne Scars

Acne can leave behind uneven skin texture and deep scars. Plenhyage XL promotes tissue repair and cellular regeneration, helping to smooth out post-acne depressions and improve overall skin texture.

  1. Hyperpigmentation and Dark Spots

Uneven skin tone and dark patches caused by sun exposure or melanin overproduction can be effectively treated with Plenhyage XL. It helps to balance pigmentation, creating a more uniform and radiant complexion.

  1. Fine Lines & Wrinkles

Combat early signs of aging with this powerful treatment. Plenhyage XL visibly reduces fine lines and superficial wrinkles by increasing skin elasticity and collagen synthesis.

  1. Forehead Lines & Frown Lines

Dynamic wrinkles between the brows and on the forehead can become more prominent over time. Plenhyage XL works to smooth and relax these expression lines, restoring a more youthful appearance.

  1. Crow’s Feet

Delicate skin around the eyes is prone to fine lines known as crow’s feet. This treatment targets these lines directly, improving hydration and skin quality around the eyes.

  1. Rosacea and Sensitive Skin

For those dealing with rosacea or inflammation-prone skin, Plenhyage XL provides a soothing effect. It helps reduce redness, irritation, and supports healthier skin barrier function.

  1. Neck Aging

The neck is often one of the first areas to show signs of aging, such as sagging, fine lines, and crepey skin. Plenhyage XL boosts firmness and elasticity in this often-overlooked area, resulting in a smoother, more youthful neck contour.

  1. Sun-Damaged Skin

Prolonged UV exposure leads to premature aging, spots, and rough texture. Plenhyage XL helps reverse sun damage, restoring skin vitality and improving overall tone and texture.

  1. Melasma

Melasma appears as patchy, uneven pigmentation, often triggered by hormonal changes and sun exposure. Plenhyage XL aids in lightening these dark patches and evening the skin tone with continued use.

  1. Dark Circles & Under-Eye Bags

The under-eye area is delicate and prone to discoloration and puffiness. Plenhyage XL revitalizes this area by reducing pigmentation, minimizing puffiness, and improving skin firmness for a more refreshed look.

At our aesthetic clinic, we offer Plenhyage XL in two carefully formulated strengths to suit a wide range of skin concerns. Whether you’re looking to refresh tired eyes or target deeper lines and acne scars, there’s a solution tailored for you.

Plenhyage XL Medium (20mg/ml)

This gentle yet effective formulation is ideal for clients seeking mild anti-aging treatments or general skin revitalization. It’s particularly beneficial for:

  • Dark circles under the eyes
  • Early signs of aging
  • Dry/tired under eye area

Plenhyage XL Strong (25mg/ml)

Designed to address more advanced skin concerns, this higher concentration is suitable for:

  • Deep wrinkles and expression lines
  • Acne scars and post-inflammatory marks
  • Sun-damaged or pigmented skin
  • Body areas such as the hands and knees, where the skin is thicker and often neglected

Plenhyage XL Strong delivers more intensive results, making it ideal for clients seeking visible rejuvenation and correction of deeper skin imperfections.

Why Choose Plenhyage XL? Clinically Proven Skin Benefits

Plenhyage XL isn’t just another cosmetic treatment—it’s backed by research and clinically proven to regenerate and restore skin health. Clinical trials have shown:

  • +115% increase in skin hydration
  • Over 50% boost in skin thickness
  • +47% improvement in collagen production
  • +38% enhancement in skin elasticity
  • Reduction in redness and inflammation, supporting treatment for rosacea and acne
  • Noticeable improvement in acne scars
  • Reduction of sun-induced pigmentation

How Does Plenhyage Work?

The magic behind Plenhyage lies in its polynucleotide-based formula. Polynucleotides are biological molecules that activate tired or damaged cells to regenerate themselves. Here’s how it works:

  1. Fibroblast Activation: Fibroblasts are cells responsible for producing collagen and elastin. Plenhyage stimulates these cells to repair tissue and restore skin elasticity.
  2. Hydration Boost: polynucleotides attract water molecules into the skin, providing intense hydration that plumps and smooths the skin.
  3. Anti-Free Radical Action: The treatment combats oxidative stress by neutralising harmful free radicals. This creates an optimal environment for cellular regeneration.
  4. Collagen Production: By increasing collagen synthesis, Plenhyage enhances skin firmness and reduces visible signs of ageing.

Clinical studies have shown remarkable results after treatment with Plenhyage. Patients experienced a 115% increase in hydration levels and a 38% improvement in elasticity within weeks of treatment. These effects make it an excellent choice for anyone seeking long-lasting skin rejuvenation.

What Can You Expect During Treatment?

A typical Plenhyage session lasts about 30 minutes. Before the procedure begins, a topical anaesthetic cream is applied to minimise discomfort. The injectable gel is then carefully administered into targeted areas by a fully registered Instabeauty Aesthetic nurse.

Post-treatment recovery is quick, most patients experience mild swelling or redness that subsides within 24–36 hours. Small bumps (product injected) may appear temporarily but will resolve shortly after the procedure. Results typically become visible within 90 days as your skin regenerates naturally.

For optimal results, most individuals require 3 sessions spaced 3/4 weeks apart. Maintenance treatments every nine months can help sustain the rejuvenating effects.

At A Glance

Procedure Time

45 minutes

Anaesthetic

Numbing cream can be applied

Target

Fine lines, wrinkles, skin hydration, and texture

Risks & Complications

Mild swelling/redness, rare allergic reactions

Downtime

Minimal

Results

Improved skin texture and elasticity over weeks to months

Treatment needed

2-4 sessions for optimal results

Not Suitable For

Pregnant, breast-feeding individuals, or those receiving IVF treatment

Why Choose Instabeauty Aesthetics in Cambridge for Aesthetic Treatment?

At Instabeauty Aesthetics, we are passionate about helping you achieve your aesthetic goals with safe and effective treatments customised to your needs. Located in Thoday Street in Cambridge with free parking facilities available, our aesthetic clinic offers a welcoming environment where you can feel confident in our expertise.

Here’s why Instabeauty Aesthetics stands out:

  • Expert Care: Our team is fully insured, complications-trained, and dedicated to delivering exceptional results.
  • Personalised Treatments: We provide free professional advice to create bespoke treatment plans that suit your unique requirements.
  • Wide Range of Services: In addition to Plenhyage treatments, we specialise in dermal fillers, microneedling, anti-wrinkle injections, and more.
  • Patient-Centric Approach: Our empathetic practitioners ensure every appointment is comfortable and enjoyable—perfect for those nervous about aesthetic procedures.

Why Add Plenhyage to Your Routine?

Plenhyage is ideal for individuals seeking natural-looking results without invasive surgery. Whether you’re battling acne scars or aiming to restore youthful radiance to your skin, this regenerative treatment offers unparalleled benefits:

  • Long-lasting effects
  • Minimal downtime
  • Suitable for sensitive areas like under-eye regions
  • Effective for both men and women

Plenhyage Before and After

Ready to Try Plenhyage?

If you are living in Cambridge or the surrounding areas, we would love to welcome you to InstaBeauty Aesthetics, which is a leading aesthetic clinic in Cambridge. Whether you are new to aesthetic treatments or looking to level up your skin routine, our expert team is always here to guide you every step of the way.

Book a consultation today to find out if Plenhyage treatment is right option for you. Let’s help you glow from the inside out — naturally.

InstaBeauty Aesthetics, Cambridge, UK

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